Article
MD-ALL: an integrative platform for molecular diagnosis of B-acute lymphoblastic leukemia.
Haematologica - 1 Jun 2024
Hu Zunsong, Jia Zhilian, Liu Jiangyue, Mao Allen, Han Helen, Gu Zhaohui
Abstract excerpt
B-acute lymphoblastic leukemia (B-ALL) consists of dozens of subtypes defined by distinct gene expression profiles (GEP) and various genetic lesions. With the application of transcriptome sequencing (RNA sequencing [RNA-seq]), multiple novel subtypes have been identified, which lead to an advanced B-ALL classification and risk-stratification system. However, the complexity of analyzing RNA-seq data for B-ALL...
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