Article

Multi-cohort transcriptomic subtyping of B-cell acute lymphoblastic leukemia

2022-02-19

Abstract excerpt

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer and comprises multiple genetically distinguishable subtypes. To detect subtypes, current pipelines include fusion calling, polymorphisms, candidate gene copy numbers and cytogenetics but these approaches have limitations. RNA-seq provides a functional genome-wide snapshot that enables classification of ALL subtypes, however, typical mRNA-seq cl...

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Literature Corpus work: 7fd5e4a7-796b-5bfc-aa3b-acd20cf2f5fd
DOI: 10.1101/2022.02.17.22270919

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