Article
Genetic profile of primary plasma cell leukemia in Korea: comparison with plasma cell myeloma.
Leukemia & lymphoma - 1 Feb 2022
Lee Youngeun, Yun Jiwon, Jeong Dajeong, Ryu Sohee, Kwon Seok Ryun, Yun Hongseok, Kim Sung Min, Park Jae Hyeon, Lee Dong Soon
Abstract excerpt
Plasma cell leukemia (PCL) is clinically and genetically distinct from multiple myeloma (MM), despite controversies regarding the disease definition. To determine the distinct features of PCL, the genetic property of primary PCL (pPCL) was compared with that of secondary PCL (sPCL) and MM. In patients with pPCL, Eighty-nine non-synonymous mutations were observed in 68 genes. The most frequently mutated genes were...
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