Article
Primary plasma cell leukemia 2.0: advances in biology and clinical management.
Expert review of hematology - 1 Nov 2016
Neri Antonino, Todoerti Katia, Lionetti Marta, Simeon Vittorio, Barbieri Marzia, Nozza Filomena, Vona Gabriella, Pompa Alessandra, Baldini Luca, Musto Pellegrino
Abstract excerpt
INTRODUCTION: Primary plasma cell leukemia (PPCL) is a rare and aggressive variant of multiple myeloma. The introduction of novel agents and modern technologies has recently partially changed the clinical and biological scenario of this malignancy, allowing limited, but not negligible, progresses. Areas covered: We will discuss: the complex landscape of genetic alterations in PPCL, derived from conventional and...
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