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Article

High-Density Lipoprotein 3 Cholesterol and Primary Open-Angle Glaucoma: Metabolomics and Mendelian Randomization Analyses.

Ophthalmology - 1 Mar 2022

Nusinovici Simon, Li Hengtong, Thakur Sahil, Baskaran Mani, Tham Yih-Chung, Zhou Lei, Sabanayagam Charumathi, Aung Tin, Silver David, Fan Qiao, Wong Tien Yin, Crowston Jonathan, Cheng Ching-Yu

Abstract excerpt

PURPOSE: We hypothesized that the effect of blood lipid-related metabolites on primary open-angle glaucoma (POAG) would differ according to specific lipoprotein particles and lipid sub-fractions. We investigated the associations of blood levels of lipoprotein particles and lipid sub-fractions with POAG. DESIGN: Cross-sectional study. PARTICIPANTS: Individuals recruited for the baseline visit of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34592243
DOI: 10.1016/j.ophtha.2021.09.013

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