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Article

Habitual Coffee Consumption Increases Risk of Primary Open-Angle Glaucoma: A Mendelian Randomization Study.

Ophthalmology - 1 Sept 2022

Li Xi, Cheng Shiming, Cheng Jingdan, Wang Mengting, Zhong Yiming, Yu A-Yong

Abstract excerpt

PURPOSE: To explore whether there is a causal relationship between coffee consumption and primary open-angle glaucoma (POAG). DESIGN: Two-sample Mendelian randomization (MR). PARTICIPANTS: The single-nucleotide polymorphisms (SNPs) associated with coffee consumption (including phenotypes 1 and 2) were selected from a genome-wide association study (GWAS) involving 121 824 individuals of European descent. Coffee...

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PMID: 35537532
DOI: 10.1016/j.ophtha.2022.04.027

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