Article
Proteomic analysis identifies novel binding partners of BAP1.
PloS one - 1 Jan 2021
Baas Roy, J van der Wal Fenna, Bleijerveld Onno B, van Attikum Haico, Sixma Titia K
Abstract excerpt
BRCA1-associated protein 1 (BAP1) is a tumor suppressor and its loss can result in mesothelioma, uveal and cutaneous melanoma, clear cell renal cell carcinoma and bladder cancer. BAP1 is a deubiquitinating enzyme of the UCH class that has been implicated in various cellular processes like cell growth, cell cycle progression, ferroptosis, DNA damage response and ER metabolic stress response. ASXL proteins activate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
