Article
ESR1 gene variants affect FSHR-depended risk of fibrocystic mastopathy in infertile women.
Experimental oncology - 1 Sept 2021
Kornatska A G, Rossokha Z I, Fishchuk L Ye, Dubenko O D, Medvedieva N L, Flaksemberg М А, Chubei G V, Popova O F, Gorovenko N G
Abstract excerpt
BACKGROUND: The infertile women have an increased risk of developing benign and malignant tumors, in particular, breast cancer. Most studies have examined the role of gene variants in the risk of developing breast cancer, but there is little evidence of genetic risk factors for benign tumors. AIM: To assess the combined genetic risk of developing mastopathy in women with FSHR (rs6165, rs6166) and ESR1 (rs9340799,...
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