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Article

Cancer as a Genetic or Epigenetic Disease?

Critical reviews in eukaryotic gene expression - 1 Jan 2021

Ribatti Domenico

Abstract excerpt

Genetic analysis of cancer suggests that neoplastic cells arise through an accumulation of mutations. The introduction of sequences of mutations increase the casual complexity associated with tumor progression. The disruption of tissue architecture is the critical causal event in tumor progression, while mutations are a consequence of this disruption. The tumor microenvironment provides continuous biochemical and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 34591384
DOI: 10.1615/CritRevEukaryotGeneExpr.2021039007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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