Watch thy neighbor: cancer is a communal affair.

Abstract excerpt

Malignant transformation of an epithelium occurs within the context of a dynamically evolving tissue stroma that is composed of multiple cell types surrounded by an extracellular matrix. Because stromal-epithelial interactions regulate tissue homeostasis and can profoundly influence tumorigenesis it has been proposed that the stromal microenvironment is an epigenetic tumor modifier that can either positively or...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alkylating Agents
• Share to Carcinogens
• Share to Extracellular Matrix