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Article

Expression and clinical significance of IL7R, NFATc2, and RNF213 in familial and sporadic multiple sclerosis.

Scientific reports - 28 Sept 2021

Imani Seyedeh Zahra Hosseini, Hojati Zohreh, Khalilian Sheyda, Dehghanian Fariba, Kheirollahi Majid, Khorrami Mehdi, Shaygannejad Vahid, Mirmosayyeb Omid

Abstract excerpt

Multiple sclerosis (MS) is a chronic inflammatory and autoimmune disorder of the central nervous system characterized by myelin loss and axonal dysfunction. Increased production of inflammatory factors such as cytokines has been implicated in axon destruction. In the present study, we compared the expression level of IL7R, NFATc2, and RNF213 genes in the peripheral blood of 72 MS patients (37 familial MS, 35...

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Identifiers

PMID: 34584155
DOI: 10.1038/s41598-021-98691-5
PMCID: PMC8478940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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