Expression and clinical significance of IL7R, NFATc2, and RNF213 in familial and sporadic multiple sclerosis

Abstract excerpt

<title>Abstract</title> <p>Background Multiple sclerosis (MS) is a chronic inflammatory and autoimmune disorder of the central nervous system characterized by myelin loss and axonal dysfunction. Increased production of inflammatory factors such as cytokines has been implicated in axon destruction in myelin-less areas. In the present study, we compared the expression level of <italic>IL7R</italic>, <italic>NFATc2...

Topics

Open a Topic to create a Post that cites this publication.

• Adenosine Triphosphatases
• Age of Onset
• Disability Evaluation
• Healthy Volunteers
• Interleukin-7 Receptor alpha Subunit
• Multiple Sclerosis
• NFATC Transcription Factors
• Ubiquitin-Protein Ligases

Identifiers and source

Literature Corpus work

6ccfd196-cae4-54be-9ccf-d459cf7fc934

DOI

10.21203/rs.3.rs-256663/v1