Article
Expression of the Streptomyces coelicolor SoxR regulon is intimately linked with actinorhodin production.
Journal of bacteriology - 1 Dec 2010
Dela Cruz Rica, Gao Yang, Penumetcha Sahitya, Sheplock Rebecca, Weng Katherine, Chander Monica
Abstract excerpt
The [2Fe-2S]-containing transcription factor SoxR is conserved in diverse bacteria. SoxR is traditionally known as the regulator of a global oxidative stress response in Escherichia coli, but recent studies suggest that this function may be restricted to enteric bacteria. In the vast majority of nonenterics, SoxR is predicted to mediate a response to endogenously produced redox-active metabolites. We have...
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