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Article

DDX21, a Host Restriction Factor of FMDV IRES-Dependent Translation and Replication

3 Sept 2021

Abstract excerpt

In cells, the contributions of DEAD-box helicases (DDXs), without which cellular life is impossible, are of utmost importance. The extremely diverse roles of the nucleolar helicase DDX21, ranging from fundamental cellular processes such as cell growth, ribosome biogenesis, protein translation, protein–protein interaction, mediating and sensing transcription, and gene regulation to viral manipulation, drew our...

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PMID: 34578346
DOI: 10.3390/v13091765

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