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Dual Promoters Improve the Rescue of Recombinant Measles Virus in Human Cells

30 Aug 2021

Abstract excerpt

Reverse genetics is a technology that allows the production of a virus from its complementary DNA (cDNA). It is a powerful tool for analyzing viral genes, the development of novel vaccines, and gene delivery vectors. The standard reverse genetics protocols are laborious, time-consuming, and inefficient for negative-strand RNA viruses. A new reverse genetics platform was established, which increases the recovery...

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PMID: 34578303
DOI: 10.3390/v13091723

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