Article
Glycoproteins and their relationship to human disease.
Acta anatomica - 1 Jan 1998
Brockhausen I, Schutzbach J, Kuhns W
Abstract excerpt
Glycoproteins are proteins that carry N- and O-glycosidically-linked carbohydrate chains of complex structures and functions. N-glycan chains are assembled in the endoplasmic reticulum and the Golgi by a controlled sequence of glycosyltransferase and glycosidase processing reactions involving dolichol intermediates. The assembly of O-glycans occurs in the Golgi and does not involve dolichol. For most reactions,...
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