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Article

A Decellularized Human Limbal Scaffold for Limbal Stem Cell Niche Reconstruction.

International journal of molecular sciences - 17 Sept 2021

Polisetti Naresh, Roschinski Benjamin, Schlötzer-Schrehardt Ursula, Maier Philip, Schlunck Günther, Reinhard Thomas

Abstract excerpt

The transplantation of ex vivo expanded limbal epithelial progenitor cells (LEPCs) on amniotic membrane or fibrin gel is an established therapeutic strategy to regenerate the damaged corneal surface in patients with limbal stem cell deficiency (LSCD), but the long-term success rate is restricted. A scaffold with niche-specific structure and extracellular matrix (ECM) composition might have the advantage to...

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Identifiers

PMID: 34576227
DOI: 10.3390/ijms221810067
PMCID: PMC8471675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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