Article
Phenotypic study of a case with successful transplantation of ex vivo expanded human limbal epithelium for unilateral total limbal stem cell deficiency.
Ophthalmology - 1 Aug 2002
Grueterich Martin, Espana Edgar M, Touhami Amel, Ti Seng-Ei, Tseng Scheffer C G
Abstract excerpt
OBJECTIVE: To minimize the risk to the donor eye when a conjunctival limbal autograft is performed for unilateral total limbal stem cell deficiency (LSCD), a new approach has been reported of expanding limbal epithelial progenitor cells from a small limbal biopsy cultured on amniotic membrane (AM). Herein, we present for the first time the morphologic and phenotypic outcome of one such patient. DESIGN:...
Topics
- Adult
- Amnion
- Antigens, Surface
- Biomarkers
- Cell Adhesion Molecules
- Cells, Cultured
- Connexin 43
- Corneal Diseases
- Epithelium, Corneal
- Fluorescent Antibody Technique, Indirect
- Humans
- Integrin alpha3beta1
- Integrin alpha6beta4