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Article

The impact of age on the physical and cellular properties of the human limbal stem cell niche.

Age (Dordrecht, Netherlands) - 1 Apr 2013

Notara M, Shortt A J, O'Callaghan A R, Daniels J T

Abstract excerpt

The limbal niche in the corneoscleral junction of the eye, habitat of the limbal epithelial stem cells (LESC), facilitates corneal epithelial regeneration by providing physical support and chemical signalling. Anatomical structures within the limbus, namely, limbal epithelial crypts and focal stromal projections, are believed to function as a putative niche for LESCs. In this study, the impact of age on the...

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Identifiers

PMID: 22252434
DOI: 10.1007/s11357-011-9359-5
PMCID: PMC3592958

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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