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Article

Role of Calcium/Calcineurin Signalling in Regulating Intracellular Reactive Oxygen Species Homeostasis in Saccharomyces cerevisiae.

Genes - 25 Aug 2021

Li Guohui, Fu Wenxuan, Deng Yu, Zhao Yunying

Abstract excerpt

The calcium/calcineurin signalling pathway is required for cell survival under various environmental stresses. Using Saccharomyces cerevisiae, we explored the mechanism underlying calcium-regulated homeostasis of intracellular reactive oxygen species (ROS). We found that deletion of acyltransferase Akr1 and C-5 sterol desaturase Erg3 increased the intracellular ROS levels and cell death, and this could be...

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Identifiers

PMID: 34573294
DOI: 10.3390/genes12091311
PMCID: PMC8466207

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