Article
Prevalence of G6PD deficiency and Plasmodium falciparum parasites in asymptomatic school children living in southern Ghana.
Malaria journal - 26 Jul 2016
Amoah Linda Eva, Opong Akua, Ayanful-Torgby Ruth, Abankwa Joana, Acquah Festus K
Abstract excerpt
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked genetic disorder that results in impaired enzyme activity. Although G6PD deficiency is globally distributed it is more prevalent in malaria-endemic countries. Several mutations have been identified in the G6PD gene, which alter enzyme activity. The G6PD genotype predominantly found in sub-Saharan Africa is the G6PDB (G6PD376A) with...
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