Article
Novel antiphospholipid antibodies in autoimmune bullous diseases.
Human antibodies - 1 Jan 2014
Sagi Lior, Baum Sharon, Barzilai Ori, Ram Maya, Bizzaro Nicola, SanMarco Marielle, Shoenfeld Yehuda, Sherer Yaniv
Abstract excerpt
BACKGROUND: Pemphigus and bullous pemphigoid are two autoimmune diseases that have similar pathogenesis. Both have a genetic predisposition, which promotes the production of auto antibodies targeted against different components of the epidermal desmosome and hemidesmosome. Antiphospholipid antibodies (aPL) are heterogeneous group of antibodies found in patients with autoimmune diseases and inflammatory conditions...
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