Iron-sulfur cluster N5 is coordinated by an HXXXCXXCXXXXXC motif in the NuoG subunit of Escherichia coli NADH:quinone oxidoreductase (complex I).

doi:10.1074/jbc.M804015200

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Article

Iron-sulfur cluster N5 is coordinated by an HXXXCXXCXXXXXC motif in the NuoG subunit of Escherichia coli NADH:quinone oxidoreductase (complex I).

The Journal of biological chemistry - 19 Sept 2008

Nakamaru-Ogiso Eiko, Matsuno-Yagi Akemi, Yoshikawa Shinya, Yagi Takao, Ohnishi Tomoko

Abstract excerpt

NADH:quinone oxidoreductase (complex I) plays a central role in cellular energy metabolism, and its dysfunction is found in numerous human mitochondrial diseases. Although the understanding of its structure and function has been limited, the x-ray crystal structure of the hydrophilic part of Thermus thermophilus complex I recently became available. It revealed the localization of all redox centers, including 9...

Topics

Amino Acid Motifs
Amino Acid Sequence
Animals
Cattle
Crystallography, X-Ray
Electron Spin Resonance Spectroscopy
Electron Transport Complex I
Iron-Sulfur Proteins
Ligands
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

NADH Dehydrogenase

Oligonucleotides

Oxidation-Reduction

Sequence Homology, Amino Acid

Temperature

Source

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Identifiers

PMID: 18603533
DOI: 10.1074/jbc.M804015200
PMCID: PMC2533800

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Iron-sulfur cluster N5 is coordinated by an HXXXCXXCXXXXXC motif in the NuoG subunit of Escherichia coli NADH:quinone oxidoreductase (complex I).PMID 18603533Read ↗

Characterization of the iron-sulfur cluster N7 (N1c) in the subunit NuoG of the proton-translocating NADH-quinone oxidoreductase from Escherichia coli.Semantic proximity Read ↗

Semiquinone and cluster N6 signals in His-tagged proton-translocating NADH:ubiquinone oxidoreductase (complex I) from Escherichia coli.Semantic proximity Read ↗

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Iron-sulfur cluster N2 of the Escherichia coli NADH:ubiquinone oxidoreductase (complex I) is located on subunit NuoB.Semantic proximity Read ↗

Roles of Subunit ND2/NuoN in the Proton Pumping Coupling Mechanism of Complex I.Semantic proximity Read ↗

Catalytic importance of acidic amino acids on subunit NuoB of the Escherichia coli NADH:ubiquinone oxidoreductase (complex I).Semantic proximity Read ↗

Roles of subunit NuoK (ND4L) in the energy-transducing mechanism of Escherichia coli NDH-1 (NADH:quinone oxidoreductase).Semantic proximity Read ↗

Functional roles of four conserved charged residues in the membrane domain subunit NuoA of the proton-translocating NADH-quinone oxidoreductase from Escherichia coli.Semantic proximity Read ↗

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