Article
Digital PCR analysis of circulating tumor DNA: a biomarker for chondrosarcoma diagnosis, prognostication, and residual disease detection.
Cancer medicine - 1 Oct 2017
Gutteridge Alice, Rathbone Victoria M, Gibbons Rebecca, Bi Mark, Archard Nicholas, Davies Kate E J, Brown Jake, Plagnol Vincent, Pillay Nischalan, Amary Fernanda, O'Donnell Paul, Gupta Manu, Tirabosco Roberto, Flanagan Adrienne M, Forshew Tim
Abstract excerpt
Conventional chondrosarcoma is the most common primary bone tumor in adults. Prognosis corresponds with tumor grade but remains variable, especially for individuals with grade (G) II disease. There are currently no biomarkers available for monitoring or prognostication of chondrosarcoma. Circulating tumor DNA (ctDNA) has recently emerged as a promising biomarker for a broad range of tumor types. To date, little...
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