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Article

Assessing the genetic relationship between gastro-esophageal reflux disease and risk of COVID-19 infection.

Human molecular genetics - 3 Feb 2022

Ong Jue-Sheng, Gharahkhani Puya, Vaughan Thomas L, Whiteman David, Kendall Bradley J, MacGregor Stuart

Abstract excerpt

Symptoms related with gastro-esophageal reflux disease (GERD) were previously shown to be linked with increased risk for the 2019 coronavirus disease (COVID-19). We aim to interrogate the possibility of a shared genetic basis between GERD and COVID-19 outcomes. Using published GWAS data for GERD (78 707 cases; 288 734 controls) and COVID-19 susceptibility (up to 32 494 cases; 1.5 million controls), we examined...

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Identifiers

PMID: 34553760
DOI: 10.1093/hmg/ddab253
PMCID: PMC8522419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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