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Epigenetic Biomarkers in Cell-Free DNA and Applications in Liquid Biopsy

9 Jan 2019

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Cell-free circulating DNA (cfDNA) in plasma has gained global interest as a diagnostic material for noninvasive prenatal testing and cancer diagnosis, or the so-called "liquid biopsy". Recent studies have discovered a great number of valuable genetic and epigenetic biomarkers for cfDNA-based liquid biopsy. Considering that the genetic biomarkers, e.g., somatic mutations, usually vary from case to case in most...

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PMID: 30634483
DOI: 10.3390/genes10010032

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