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Article

Neutral evolution test of the spike protein of SARS-CoV-2 and its implications in the binding to ACE2.

Scientific reports - 22 Sept 2021

López-Cortés Georgina I, Palacios-Pérez Miryam, Zamudio Gabriel S, Veledíaz Hannya F, Ortega Enrique, José Marco V

Abstract excerpt

As the SARS-CoV-2 has spread and the pandemic has dragged on, the virus continued to evolve rapidly resulting in the emergence of new highly transmissible variants that can be of public health concern. The evolutionary mechanisms that drove this rapid diversity are not well understood but neutral evolution should open the first insight. The neutral theory of evolution states that most mutations in the nucleic...

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Identifiers

PMID: 34552110
DOI: 10.1038/s41598-021-96950-z
PMCID: PMC8458503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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