Article

Functional evolution of SARS-COV-2 Spike protein: adaptation on translation and infection via surface charge of spike protein

2022-05-16

Abstract excerpt

The SARS-COV-2 virus, which causes the COVID-19, is rapidly accumulating mutations to adapt to the hosts. We collected SARS-COV-2 sequence data from the end of 2019 to April 2022 to analyze for their evolutionary features during the pandemic. We found that most of the SARS-COV-2 genes are undergoing negative purifying selection, while the spike protein gene (S-gene) is undergoing rapid positive selection. From the...

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Literature Corpus work: e3c13694-33a5-5c8a-a5a6-4b60586929ad
DOI: 10.1101/2022.05.16.492062

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