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Article

Rapid and label-free amplification and detection assay for genotyping of cancer biomarker.

Biosensors & bioelectronics - 15 Jun 2015

Shin Yong, Soo Ross A, Yoon Jaeyun, Promoda Perera Agampodi, Yoon Yong-Jin, Park Mi Kyoung

Abstract excerpt

As understanding of the molecular pathways that drive malignancy in human cancer improves, personalized genotype-based therapy in combination with the predictive biomarker for the efficacy of targeted therapy is becoming more popular in cancer management. Sanger sequencing, that has been the gold standard for mutation analysis in cancer since the 1970s, suffers from low sensitivity, complexity, and time-consuming...

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Identifiers

PMID: 25569872
DOI: 10.1016/j.bios.2014.12.039

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EGFR

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