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Microglia and BDNF at the crossroads of stressor related disorders: Towards a unique trophic phenotype.

Neuroscience and biobehavioral reviews - 1 Dec 2021

Prowse Natalie, Hayley Shawn

Abstract excerpt

Stressors ranging from psychogenic/social to neurogenic/injury to systemic/microbial can impact microglial inflammatory processes, but less is known regarding their effects on trophic properties of microglia. Recent studies do suggest that microglia can modulate neuronal plasticity, possibly through brain derived neurotrophic factor (BDNF). This is particularly important given the link between BDNF and...

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PMID: 34537262
DOI: 10.1016/j.neubiorev.2021.09.018

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