Article
Pharmacogenetics of second-generation antipsychotics.
Pharmacogenomics - 1 Apr 2014
Brennan Mark D
Abstract excerpt
This review considers pharmacogenetics of the so called 'second-generation' antipsychotics. Findings for polymorphisms replicating in more than one study are emphasized and compared and contrasted with larger-scale candidate gene studies and genome-wide association study analyses. Variants in three types of genes are discussed: pharmacokinetic genes associated with drug metabolism and disposition, pharmacodynamic...
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