Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

APOBEC3C, a nucleolar protein induced by genotoxins, is excluded from DNA damage sites.

The FEBS journal - 1 Feb 2022

Constantin Daniel, Dubuis Gilles, Conde-Rubio María Del Carmen, Widmann Christian

Abstract excerpt

The human genome contains 11 APOBEC (apolipoprotein B mRNA editing catalytic polypeptide-like) cytidine deaminases classified into four families. These proteins function mainly in innate antiviral immunity and can also restrict endogenous retrotransposable element multiplication. The present study focuses on APOBEC3C (A3C), a member of the APOBEC3 subfamily. Some APOBEC3 proteins use their enzymatic activity on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Nucleolus
Share to Cytidine Deaminase
Share to DNA Breaks, Double-Stranded

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA End-Joining Repair

Share to Etoposide

Share to Homologous Recombination

Share to Multigene Family

Share to Mutagens

Source

Open in PubMed Open full text

Identifiers

PMID: 34528388
DOI: 10.1111/febs.16202
PMCID: PMC9292673

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

APOBEC3C, a nucleolar protein induced by genotoxins, is excluded from DNA damage sites.PMID 34528388Read ↗

Human APOBEC3A Isoforms Translocate to the Nucleus and Induce DNA Double Strand Breaks Leading to Cell Stress and DeathSemantic proximity Read ↗

APOBEC3A damages the cellular genome during DNA replicationSemantic proximity Read ↗

The Cytidine Deaminase APOBEC3 Family Is Subject to Transcriptional Regulation by p53.Semantic proximity Read ↗

APOBEC3G rescues cells from the deleterious effects of DNA damageSemantic proximity Read ↗

Methylcytosine and Normal Cytosine Deamination by the Foreign DNA Restriction Enzyme APOBEC3ASemantic proximity Read ↗

The interesting relationship between APOBEC3 deoxycytidine deaminases and cancer: a long road ahead.Semantic proximity Read ↗

APOBEC3 Proteins: From Antiviral Immunity to Oncogenic Drivers in HPV-Positive CancersSemantic proximity Read ↗

Retroelements versus APOBEC3 family members: No great escape from the magnificent sevenSemantic proximity Read ↗

APOBEC3 family proteins as drivers of virus evolutionSemantic proximity Read ↗

Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancerSemantic proximity Read ↗

The Intricate Interplay between APOBEC3 Proteins and DNA Tumour VirusesSemantic proximity Read ↗

Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.