Article
Identification of persistent and resolving subphenotypes of acute hypoxemic respiratory failure in two independent cohorts.
Critical care (London, England) - 15 Sept 2021
Sathe Neha A, Zelnick Leila R, Mikacenic Carmen, Morrell Eric D, Bhatraju Pavan K, McNeil J Brennan, Kosamo Susanna, Hough Catherine L, Liles W Conrad, Ware Lorraine B, Wurfel Mark M
Abstract excerpt
BACKGROUND: Acute hypoxemic respiratory failure (HRF) is associated with high morbidity and mortality, but its heterogeneity challenges the identification of effective therapies. Defining subphenotypes with distinct prognoses or biologic features can improve therapeutic trials, but prior work has focused on ARDS, which excludes many acute HRF patients. We aimed to characterize persistent and resolving...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.