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Modulating Tumor Microenvironment: A Review on STK11 Immune Properties and Predictive vs Prognostic Role for Non-small-cell Lung Cancer Immunotherapy.

Current treatment options in oncology - 15 Sept 2021

Mazzaschi Giulia, Leonetti Alessandro, Minari Roberta, Gnetti Letizia, Quaini Federico, Tiseo Marcello, Facchinetti Francesco

Abstract excerpt

OPINION STATEMENT: The quest for immunotherapy (IT) biomarkers is an element of highest clinical interest in both solid and hematologic tumors. In non-small-cell lung cancer (NSCLC) patients, besides PD-L1 expression evaluation with its intrinsic limitations, tissue and circulating parameters, likely portraying the tumor and its stromal/immune counterparts, have been proposed as potential predictors of IT...

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PMID: 34524570
DOI: 10.1007/s11864-021-00891-8

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