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<i>STK11</i> and <i>KEAP1</i> Mutations as Prognostic Biomarkers in an Observational Real-World Lung Adenocarcinoma Cohort

2020-01-27

Abstract excerpt

<h4>Importance</h4> Understanding the mechanisms of primary resistance to immune checkpoint blockade therapy is of paramount importance for treatment selection. Somatic mutations in STK11 and KEAP1 , frequently co-mutated in nonsquamous non–small cell lung cancer, have been associated with poor response to immune checkpoint blockade. However, previous reports lack non–immune checkpoint blockade controls needed to...

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Literature Corpus work
d7d3f36c-cb5b-5579-a522-4445e6d9f9bf
DOI
10.1101/2020.01.23.20017566
Open publication

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<i>STK11</i> and <i>KEAP1</i> Mutations as Prognostic Biomarkers in an Observational Real-World Lung Adenocarcinoma CohortDOI 10.1101/2020.01.23.20017566
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