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STK11 mutation affects tumor proliferation by impacting CD4+ T cell activity in lung adenocarcinoma

28 Oct 2024

Abstract excerpt

Introduction STK11 mutation is common in lung adenocarcinoma (LUAD), but the molecular mechanism of STK11 regulation in LUAD remains uncharacterized. This study intended to explore the effect of STK11 mutation on activity and proliferation of CD4+ T cells in LUAD. Material and methods qRT-PCR experiments verified the STK11 level in different cell models. Cell Counting Kit-8 (CCK-8) and colony formation...

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PMID: 39720276
DOI: 10.5114/ceji.2024.143578

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