Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The expression and activity of Toll-like receptors in the preimplantation human embryo suggest a new role for innate immunity

23 Jul 2021

Abstract excerpt

STUDY QUESTION: Is the innate immunity system active in early human embryo development? SUMMARY ANSWER: The pattern recognition receptors and innate immunity Toll-like receptor (TLR) genes are widely expressed in preimplantation human embryos and the pathway appears to be active in response to TLR ligands. WHAT IS KNOWN ALREADY: Early human embryos are highly sensitive to their local environment, however...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Response and Inflammation
Share to Preterm Birth and Chorioamnionitis
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34517414
DOI: 10.1093/humrep/deab188

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The expression and activity of Toll-like receptors in the preimplantation human embryo suggest a new role for innate immunityPMID 34517414Read ↗

TLR signaling pathway and the effects of main immune cells and epigenetics factors on the diagnosis and treatment of infertility and sterilitySemantic proximity Read ↗

Toll-like receptor 4 activation on human amniotic epithelial cells is a risk factor for pregnancy lossSemantic proximity Read ↗

Soluble Ligands and Their Receptors in Human Embryo Development and ImplantationSemantic proximity Read ↗

Activation of Toll-Like Receptors Differentially Modulates Inflammation in the Human Reproductive Tract: Preliminary Findings.Semantic proximity Read ↗

Complement in Human Pre-implantation Embryos: Attack and DefenseSemantic proximity Read ↗

Complement in human pre-implantation embryos: attack and defenseSemantic proximity Read ↗

Use of murine embryonic fibroblasts to define Toll-like receptor activation and specificitySemantic proximity Read ↗

Use of murine embryonic fibroblasts to define Toll-like receptor activation and specificitySemantic proximity Read ↗

Expression and Activity of Toll-Like Receptors 1–9 in the Human Term Placenta and Changes Associated with Labor at TermSemantic proximity Read ↗

The Role of Danger Associated Molecular Patterns in Human Fetal Membrane WeakeningSemantic proximity Read ↗

Differential expression of toll-like receptors in the human placenta across early gestationSemantic proximity Read ↗

Effects of endometrial embryokines on the preimplantation bovine embryo to create a gene expression signature consistent with a high competence phenotype†.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.