Article
Activation of Toll-Like Receptors Differentially Modulates Inflammation in the Human Reproductive Tract: Preliminary Findings.
Frontiers in immunology - 1 Jan 2020
Benjelloun Fahd, Quillay Héloïse, Cannou Claude, Marlin Romain, Madec Yoann, Fernandez Hervé, Chrétien Fabrice, Le Grand Roger, Barré-Sinoussi Françoise, Nugeyre Marie-Thérèse, Menu Elisabeth
Abstract excerpt
The female reproductive tract (FRT) is the main site of entry of sexually transmitted infections (STIs). Toll-like receptors (TLRs) that recognize pathogenic motifs are widely expressed in the FRT. TLR stimulation induces immune activation and local production of inflammatory mediators. In the FRT, this response should also be compatible with reproductive functions and symbiosis with host microbiota. With a view...
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