Article
Neuromedin U induces an invasive phenotype in CRC cells expressing the NMUR2 receptor.
Journal of experimental & clinical cancer research : CR - 7 Sept 2021
Przygodzka Patrycja, Sochacka Ewelina, Soboska Kamila, Pacholczyk Marcin, Papiewska-Pająk Izabela, Przygodzki Tomasz, Płociński Przemysław, Ballet Steven, De Prins An, Boncela Joanna
Abstract excerpt
BACKGROUND: Successful colorectal cancer (CRC) therapy often depends on the accurate identification of primary tumours with invasive potential. There is still a lack of identified pathological factors associated with disease recurrence that could help in making treatment decisions. Neuromedin U (NMU) is a secretory neuropeptide that was first isolated from the porcine spinal cord, and it has emerged as a novel...
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