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Article

MicroRNA-101 (miR-101) post-transcriptionally regulates the expression of EP4 receptor in colon cancers

1 Feb 2012

Abstract excerpt

PURPOSE: Expression of the PGE2 receptor, EP4, is up-regulated during colorectal carcinogenesis. However the mechanism leading to deregulation of the EP4 receptor is not known. The present study was conducted to investigate the regulation of EP4 receptor by miRNAs. EXPERIMENTAL DESIGN: We analyzed 26 colon cancers (i.e. 15 adenocarcinomas and 9 adenomas) and 16 normal colon specimens for EP4 receptor expression...

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PMID: 22353936
DOI: 10.4161/cbt.13.3.18874

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