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Article

The role of the HLA allelic repertoire on the clinical severity of COVID-19 in Canadians, living in the Saskatchewan province.

Human immunology - 1 Mar 2023

Kakodkar Pramath, Dokouhaki Pouneh, Wu Fang, Shavadia Jay, Nair Revathi, Webster Destinie, Sawyer Terry, Huan Tao, Mostafa Ahmed

Abstract excerpt

AIMS: The HLA system has been implicated as an underlying determinant for modulating the immune response to SARS-CoV-2. In this study, we aimed to determine the association of patients' HLA genetic profiles with the disease severity of COVID-19 infection. METHODS: Prospective study was conducted on COVID-19 patients (n = 40) admitted to hospitals in Saskatoon, Canada, between March and December 2020....

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Identifiers

PMID: 36707385
DOI: 10.1016/j.humimm.2023.01.003
PMCID: PMC9852320

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