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LGR6 activates the Wnt/β-catenin signaling pathway and forms a β-catenin/TCF7L2/LGR6 feedback loop in LGR6high cervical cancer stem cells

6 Sept 2021

Abstract excerpt

Abstract The leucine-rich repeat-containing G-protein-coupled receptor 6 (LGR6) is considered to be a stem cell marker in many normal tissues and promotes tissue development, regeneration, and repair. LGR6 is also related to the initiation and progression of some malignant tumors. However, the role of LGR6 in cervical cancer has not been reported. Here, immunohistochemistry and western blotting showed that LGR6...

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PMID: 34489551
DOI: 10.1038/s41388-021-02002-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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