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Translational models of 3-D organoids and cancer stem cells in gastric cancer research

6 Sept 2021

Abstract excerpt

It is postulated as a general concept of cancer stem cells (CSCs) that they can produce cancer cells overtly and repopulate cancer progenitor cells indefinitely. The CSC niche is part of a specialized cancer microenvironment that is important to keep the phenotypes of CSCs. Stem cell- and induced pluripotent stem cell (iPSC)-derived organoids with genetic manipulation are beneficial to the investigation of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34488885
DOI: 10.1186/s13287-021-02521-4

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