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Article

Multi-parametric MRI phenotype with trustworthy machine learning for differentiating CNS demyelinating diseases.

Journal of translational medicine - 6 Sept 2021

Huang Jing, Xin Bowen, Wang Xiuying, Qi Zhigang, Dong Huiqing, Li Kuncheng, Zhou Yun, Lu Jie

Abstract excerpt

BACKGROUND: Misdiagnosis of multiple sclerosis (MS) and neuromyelitis optica (NMO) may delay the treatment, resulting in poor prognosis. However, the precise identification of these two diseases is still challenging in clinical practice. We aimed to evaluate the value of quantitative radiomic features extracted from the brain white matter lesions for differential diagnosis of MS and NMO. METHODS: We recruited 116...

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Identifiers

PMID: 34488799
DOI: 10.1186/s12967-021-03015-w
PMCID: PMC8419989

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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