Article
Pediatric Metastatic Hepatoblastoma With an ARID1A Mutation and Rhabdoid Cells.
International journal of surgical pathology - 1 May 2022
Alturkustani Murad, Gallant Rachel, Raca Gordana, Ranganathan Sarangarajan, Mahabir Roshan, Biegel Jaclyn A, Mascarenhas Leo, Moke Diana, Szymanski Linda J
Abstract excerpt
The small cell undifferentiated component of hepatoblastoma is an uncommon histologic component and is distinguished from small cell undifferentiated like pattern (originally called hepatoblastoma and now recognized to be malignant rhabdoid tumor) by the bi-allelic SMARCB1 mutations or copy number alterations in the latter. AT-rich interactive domain-containing protein 1A (ARID1A) is a part of the ATP-dependent...
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