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Macrophages target Listeria monocytogenes by two discrete non-canonical autophagy pathways

5 Sept 2021

Abstract excerpt

Non-canonical autophagy pathways decorate single-membrane vesicles with Atg8-family proteins such as MAP1LC3/LC3 (microtubule-associated protein 1 light chain 3). Phagosomes containing the bacterial pathogen Listeria monocytogenes (L.m.) can be targeted by a non-canonical autophagy pathway called LC3-associated phagocytosis (LAP), which substantially contributes to the anti-listerial activity of macrophages and...

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PMID: 34482812
DOI: 10.1080/15548627.2021.1969765

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