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Autophagy and checkpoints for intracellular pathogen defense

12 Nov 2014

Abstract excerpt

PURPOSE OF REVIEW: Autophagy plays a crucial role in intracellular defense against various pathogens. Xenophagy is a form of selective autophagy that targets intracellular pathogens for degradation. In addition, several related, yet distinct, intracellular defense responses depend on autophagy-related genes. This review gives an overview of these processes, pathogen strategies to subvert them, and their crosstalk...

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PMID: 25394238
DOI: 10.1097/mog.0000000000000134

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