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Annotated expression and activity data for murine recombinase alleles and transgenes: the CrePortal resource.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 2022

Perry Michelle N, Smith Constance M, Onda Hiroaki, Ringwald Martin, Murray Stephen A, Smith Cynthia L

Abstract excerpt

Recombinase alleles and transgenes can be used to facilitate spatio-temporal specificity of gene disruption or transgene expression. However, the versatility of this in vivo recombination system relies on having detailed and accurate characterization of recombinase expression and activity to enable selection of the appropriate allele or transgene. The CrePortal ( http://www.informatics.jax.org/home/recombinase )...

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PMID: 34482425
DOI: 10.1007/s00335-021-09909-w
PMCID: PMC8913597

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