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Article

Mutations in the calcium-sensing receptor: a new genetic risk factor for chronic pancreatitis?

Scandinavian journal of gastroenterology - 1 Mar 2006

Felderbauer P, Klein W, Bulut K, Ansorge N, Dekomien G, Werner I, Epplen J T, Schmitz F, Schmidt W E

Abstract excerpt

OBJECTIVE: In 2003 we identified a family with familial hypocalciuric hypercalcemia (FHH) (heterozygous CASR gene mutation L173P) and a mutation in the pancreatic secretory trypsin inhibitor gene (SPINK1) (N34S). While family members with an isolated calcium-sensing receptor gene (CASR) mutation remained healthy, a combination of the CASR and SPINK1 gene mutation caused chronic pancreatitis (CP). We thus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Trypsin Inhibitor, Kazal Pancreatic

Source

Identifiers

PMID: 16497624
DOI: 10.1080/00365520510024214

Genes

CASR
SPINK1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Mutations in the calcium-sensing receptor: a new genetic risk factor for chronic pancreatitis?PMID 16497624Read ↗

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Novel mutations in the calcium sensing receptor gene in tropical chronic pancreatitis in India.Semantic proximity Read ↗

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