Article
Genetic risk factors for pancreatic disorders.
Gastroenterology - 1 Jun 2013
Whitcomb David C
Abstract excerpt
A combination of genetic, environmental, and metabolic factors contribute to the development and recurrence of acute and chronic pancreatitis; information on all of these is required to manage patients effectively. For example, variants that affect regulation of the protease, serine (PRSS)1-PRSS2, and claudin (CLDN)2 loci, rather than their coding sequences, interact with other genetic and environmental factors...
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